Third year student in Clinical Neurosciences
The majority of people with multiple sclerosis (MS) develop a secondary progressive form of disease characterised by irreversible accumulation of damage and disability. My PhD research has been focused on developing a novel source of neural stem cells, which can be obtained directly from skin cells of affected individuals. I have shown that directly induced neural stem cells can heal mouse models of progressive MS by turning down the detrimental activation of immune cells and replacing the cells that wrap the damaged nerves. These findings open a new era of personalised stem cell medicines for progressive MS patients.